169. Patterned Substrate-Mediated DNA Delivery Using Soft Lithography for Neural Tissue Engineering

Approaches to neural tissue engineering using scaffolds for drug delivery.

This review seeks to give an overview of the current approaches to drug delivery from scaffolds for neural tissue engineering applications. The challenges presented by attempting to replicate the three types of nervous tissue (brain, spinal cord, and peripheral nerve) are summarized. Potential scaffold materials (both synthetic and natural) and target drugs are discussed with the benefits and d...

Capillary force lithography for cardiac tissue engineering.

Cardiovascular disease remains the leading cause of death worldwide(1). Cardiac tissue engineering holds much promise to deliver groundbreaking medical discoveries with the aims of developing functional tissues for cardiac regeneration as well as in vitro screening assays. However, the ability to create high-fidelity models of heart tissue has proven difficult. The heart's extracellular matrix ...

Mirrorless lasing from mesostructured waveguides patterned by soft lithography

Mesostructured silica waveguide arrays were fabricated with a combination of acidic sol-gel block copolymer templating chemistry and soft lithography. Waveguiding was enabled by the use of a low-refractive index (1.15) mesoporous silica thin film support. When the mesostructure was doped with the laser dye rhodamine 6G, amplified spontaneous emission was observed with a low pumping threshold of...

Interference Lithography for Patterned Media

Fabrication of polymeric microparticles for drug delivery by soft lithography.

Soft lithographic techniques were used to fabricate polymeric microparticles for drug delivery applications. The microparticles were made of thermoplastics and thermosets from different types of precursors including reactive resin and polymer solutions in organic solvents or water. The microparticles produced using these methods were made of widely used polymers for drug delivery with highly un...